Plasma Donation Requirements

If you’re interested in donating plasma and platelets, you may wonder whether you’re eligible.

Those in good health who meet the plasma donation requirements below are invited to schedule a first donation appointment with us.

Who Can Donate Plasma?

It’s important to note there are several rules for donating plasma. To be eligible, you must

  • Live within a 20-mile radius of a PlasmaSource donation center
  • Be between 18 and 69 years of age
  • Weigh at least 110 pounds (50 kilograms)
  • Be in good physical health
  • Test negative for transmissible infectious diseases (e.g., HIV, hepatitis, measles, flu, cold, COVID-19, etc.)
  • Disclose all current medications and medical conditions
  • Complete a health screening and physical exam (weight, blood pressure, pulse, temperature, anemia, and protein levels)
  • Complete a comprehensive medical history screening
  • Avoid taking aspirin for 48 hours before your donation
  • Be at least six months postpartum (please check with your doctor before donating)


Note: If you take any prescription medications (including hormone replacement therapies) regularly, please contact us to determine whether you meet all plasma donation requirements.

PlasmaSource also recommends all donors follow healthy lifestyle habits, such as

  • Maintaining a healthy, protein-rich diet
  • Exercising regularly
  • Getting plenty of rest (e.g., between 7-9 hours per night)
  • Avoiding substance use

What Do You Need to Donate Plasma?

In addition to meeting the plasma donation requirements above, PlasmaSource requires specific documentation to donate.

All PlasmaSource donors must have a

Government-Issued Photo ID
e.g., driver’s license or passport
Proof of Address
e.g., utility or phone bill
Proof of Social Security
e.g., W-2 form or pay stub

Schedule a donation today, earn money, and make a positive impact in your community.

What Disqualifies You from Donating Plasma?

There are several reasons you can’t donate plasma. To ensure it’s safe for medical use, you will undergo thorough testing to confirm whether your bloodwork meets all screening requirements for donating plasma.

We must rule out several infectious diseases and medications considered unsafe for plasma-based therapeutics.

You are not eligible to donate plasma or platelets if you have ever

  • Had a positive test for HIV, hepatitis B or C
  • Had an organ or bone marrow transplant
  • Had a dura mater (brain covering) graft
  • Had a transplant or medical procedure using live cells, tissues, or organs from an animal
  • Had Ebola virus disease or infection
  • Used needles to take drugs, steroids, or anything not prescribed by your doctor
  • Received money, drugs, or other payment for sex

You are not eligible to donate plasma or platelets if you have done one or more of these in the last 12 months

  • Lived (shared the same kitchen and bathroom) with a person with hepatitis
  • Had sexual contact with anyone with hepatitis
  • Received bone, tissue, or skin from another person (e.g., during surgery)
  • Have been in juvenile detention, lock up, jail, or prison for 72 (or more) consecutive hours
  • Had sexual contact with anyone who
    • Has HIV infection
    • Has ever tested positive for HIV
    • Has ever used needles to take drugs, steroids, or anything not prescribed by their doctor
    • Had sexual contact with a prostitute or anyone else who has ever taken money, drugs, or other payment for sex
    • Have been treated for syphilis or gonorrhea

You are not eligible to donate plasma or platelets if you have done one or more of these in the last four months:

  • Had a blood transfusion or received other blood products
  • Had an accidental needle stick involving exposure to blood
  • Had contact with someone else’s blood
  • Had a new tattoo, permanent make-up, microblading, piercing, or acupuncture
  • Traveled to malarial risk areas (e.g., Africa, Asia, Central and South America, Dominican Republic, Haiti, Papua New Guinea, and some Pacific Islands)

You are not eligible to donate plasma or platelets if you currently have

  • Signs or symptoms associated with acute HIV infection (e.g., fever, enlarged lymph nodes, sore throat, rash)
A picture of red blood cells.

Plasma Donation Requirements for Repeat Donors

If you stay hydrated, your plasma regenerates quickly, often within 48 hours. Because of this, you can donate twice in one week as long as donations are scheduled two days apart.

Donor safety and the safety of our plasma donations are our top priorities. If you’re in good health and meet all the requirements to donate plasma, we invite you to learn more about our donation process and schedule an appointment today.

Donating plasma is a rewarding way to give back to your community, help those in need, and earn money.

Donor eligibility is at the sole discretion of PlasmaSource.

Ready to Get Started?

Are you interested in becoming a plasma and platelet donor? Contact our our plasma donation center in Aurora, IL to schedule an appointment today.